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http://purl.uniprot.org/citations/20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20937006http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To evaluate cord blood erythropoietin (EPO) and interleukin-6 (IL-6) levels to predict preterm infants at risk of developing intraventricular hemorrhage (IVH).

Methods

Levels of umbilical cord EPO, acid-base status and IL-6 were analyzed in 116 consecutive, preterm newborns (GA at delivery: 29 [23-34 ] weeks) born to mothers who had a clinically indicated amniocentesis to rule out infection. Early-onset neonatal sepsis (EONS) was diagnosed using symptoms, hematological criteria and blood cultures.

Results

IVH was diagnosed by cranial ultrasounds. The prevalence of IVH in our population was 25% (29/116). There was a direct relationship between cord blood EPO and cord blood IL-6 concentration (r = 0.225, p = 0.014), independent of GA at birth. Elevated cord blood EPO levels (r = 0.182, p = 0.016) and GA at birth (r = -0.236, p = 0.004) remained significant independent factors associated with the risk of IVH, when evaluated with stepwise logistic regression analyses. Cord blood IL-6, pH, and EONS were not associated with IVH. These relationships remained following correction for GA at birth (p = 0.027).

Conclusions

Our results suggest that elevation in cord blood EPO may predict newborns at risk for IVH, independent of fetal inflammatory status. Further studies are warranted to confirm this association."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.org/dc/terms/identifier"doi:10.3109/14767058.2010.520048"xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Han C.S."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Lee S.Y."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Buhimschi I.A."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Bhandari V."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Buhimschi C.S."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Dulay A.T."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Oliver E.A."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Campbell K.H."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Pettker C.M."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/author"Werner E.F."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/name"J Matern Fetal Neonatal Med"xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/pages"673-679"xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/title"Cord blood erythropoietin and interleukin-6 for prediction of intraventricular hemorrhage in the preterm neonate."xsd:string
http://purl.uniprot.org/citations/20937006http://purl.uniprot.org/core/volume"24"xsd:string
http://purl.uniprot.org/citations/20937006http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20937006
http://purl.uniprot.org/citations/20937006http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20937006
http://purl.uniprot.org/uniprot/#_A0A1C9J7U0-mappedCitation-20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20937006
http://purl.uniprot.org/uniprot/#_B4DVM1-mappedCitation-20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20937006
http://purl.uniprot.org/uniprot/#_B4DNV3-mappedCitation-20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20937006
http://purl.uniprot.org/uniprot/#_B4DNQ5-mappedCitation-20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20937006
http://purl.uniprot.org/uniprot/#_B7ZKK5-mappedCitation-20937006http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20937006