| http://purl.uniprot.org/citations/21062661 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21062661 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveThe objective of the study was to determine whether eclampsia has a different circulating profile of angiogenic (placental growth factor [PlGF]) and antiangiogenic factors (soluble vascular endothelial growth factor receptor-1 [sVEGFR-1] and soluble endoglin [sEng]) from severe preeclampsia.Study designThis cross-sectional study included pregnant women in the following groups: (1) normal pregnancy (n = 40); (2) severe preeclampsia (n = 40); and (3) eclampsia (n = 20). Maternal serum PlGF, sVEGFR-1, and sEng concentrations were determined using an enzyme-linked immunosorbent assay.ResultsThe study results included the following: (1) the median concentration of sVEGFR-1 and sEng was higher and of PlGF was lower in severe preeclampsia or eclampsia than in normal pregnancy (P < .001 for all); and (2) the median concentrations of these 3 analytes did not differ significantly between patients with severe preeclampsia and those with eclampsia.ConclusionEclampsia is associated with higher maternal circulating concentrations of sVEGFR-1 and sEng and lower concentrations of PlGF than normal pregnancy but with similar concentrations to severe preeclampsia. These findings suggest that eclampsia shares a common pathogenic pathway as severe preeclampsia."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ajog.2010.08.049"xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Romero R."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Karumanchi S.A."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Hassan S.S."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Kusanovic J.P."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Sorokin Y."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Vaisbuch E."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Cotton D.B."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/author | "Whitty J.E."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/name | "Am J Obstet Gynecol"xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/pages | "152.e1-9"xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/title | "Circulating angiogenic and antiangiogenic factors in women with eclampsia."xsd:string |
| http://purl.uniprot.org/citations/21062661 | http://purl.uniprot.org/core/volume | "204"xsd:string |
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