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http://purl.uniprot.org/citations/21072061http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21072061http://www.w3.org/2000/01/rdf-schema#comment"The eukaryotic exosome is a key nuclease for the degradation, processing and quality control of a wide variety of RNAs. Here, we report electron microscopic reconstructions and pseudo-atomic models of the ten-subunit Saccharomyces cerevisiae exosome in the unbound and RNA-bound states. In the RNA-bound structures, extra density that is visible at the entry and exit sites of the exosome channel indicates that a substrate-threading mechanism is used by the eukaryotic exosome. This channelling mechanism seems to be conserved in exosome-like complexes from all domains of life, and might have been present in the most recent common ancestor."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.org/dc/terms/identifier"doi:10.1038/embor.2010.164"xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Clare D.K."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Lorentzen E."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Dziembowski A."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Basquin J."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Conti E."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Bonneau F."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Ebert J."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Saibil H.R."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Malet H."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Topf M."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Tomecki R."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/author"Drazkowska K."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/name"EMBO Rep"xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/pages"936-942"xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/title"RNA channelling by the eukaryotic exosome."xsd:string
http://purl.uniprot.org/citations/21072061http://purl.uniprot.org/core/volume"11"xsd:string
http://purl.uniprot.org/citations/21072061http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21072061
http://purl.uniprot.org/citations/21072061http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21072061
http://purl.uniprot.org/uniprot/#_P53859-mappedCitation-21072061http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21072061
http://purl.uniprot.org/uniprot/#_P46948-mappedCitation-21072061http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21072061
http://purl.uniprot.org/uniprot/#_Q08162-mappedCitation-21072061http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21072061