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http://purl.uniprot.org/citations/21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21094132http://www.w3.org/2000/01/rdf-schema#comment"It has previously been reported that shedding of the PTPκ ectodomain drives enhanced motility of colon cancer cells. Herein, we provide mechanism underlying the regulation of PTPκ shedding by galectin-3 binding protein. PTPκ was inarguably scissored by the processed form of proprotein convertase 5 (subtilisin/kexin type 5), and galectin-3 binding protein which is over-produced in colon cancer cells and tissues contributed to increased cancer cell motility by acting as a negative regulator of galectin-3 at the cell surface. The high expression ratio of galectin-3 binding protein to galectin-3 was clinically correlated to lymphatic invasion. These results suggest that galectin-3 binding protein may be a potential therapeutic target for treatment of, at least, colon cancer patients with high expression of galectin-3 binding protein."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2010.11.071"xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Kim Y.S."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Kim H.J."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Yoo J.S."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Yoo H.S."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Ko J.H."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Oh S."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Cho C."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Ahn Y.H."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/author"Jung J.A."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/pages"96-102"xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/title"Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5."xsd:string
http://purl.uniprot.org/citations/21094132http://purl.uniprot.org/core/volume"404"xsd:string
http://purl.uniprot.org/citations/21094132http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21094132
http://purl.uniprot.org/citations/21094132http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21094132
http://purl.uniprot.org/uniprot/#_A0A0S2Z3Y1-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132
http://purl.uniprot.org/uniprot/#_A0A669KA35-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132
http://purl.uniprot.org/uniprot/#_B4DDG4-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132
http://purl.uniprot.org/uniprot/#_B4DVE1-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132
http://purl.uniprot.org/uniprot/#_B4DI70-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132
http://purl.uniprot.org/uniprot/#_B4DWA8-mappedCitation-21094132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21094132