http://purl.uniprot.org/citations/21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21094132 | http://www.w3.org/2000/01/rdf-schema#comment | "It has previously been reported that shedding of the PTPκ ectodomain drives enhanced motility of colon cancer cells. Herein, we provide mechanism underlying the regulation of PTPκ shedding by galectin-3 binding protein. PTPκ was inarguably scissored by the processed form of proprotein convertase 5 (subtilisin/kexin type 5), and galectin-3 binding protein which is over-produced in colon cancer cells and tissues contributed to increased cancer cell motility by acting as a negative regulator of galectin-3 at the cell surface. The high expression ratio of galectin-3 binding protein to galectin-3 was clinically correlated to lymphatic invasion. These results suggest that galectin-3 binding protein may be a potential therapeutic target for treatment of, at least, colon cancer patients with high expression of galectin-3 binding protein."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2010.11.071"xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Kim Y.S."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Kim H.J."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Yoo J.S."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Yoo H.S."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Ko J.H."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Oh S."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Cho C."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Ahn Y.H."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/author | "Jung J.A."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/pages | "96-102"xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/title | "Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5."xsd:string |
http://purl.uniprot.org/citations/21094132 | http://purl.uniprot.org/core/volume | "404"xsd:string |
http://purl.uniprot.org/citations/21094132 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21094132 |
http://purl.uniprot.org/citations/21094132 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21094132 |
http://purl.uniprot.org/uniprot/#_A0A0S2Z3Y1-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |
http://purl.uniprot.org/uniprot/#_A0A669KA35-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |
http://purl.uniprot.org/uniprot/#_B4DDG4-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |
http://purl.uniprot.org/uniprot/#_B4DVE1-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |
http://purl.uniprot.org/uniprot/#_B4DI70-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |
http://purl.uniprot.org/uniprot/#_B4DWA8-mappedCitation-21094132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21094132 |