| http://purl.uniprot.org/citations/21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21111237 | http://www.w3.org/2000/01/rdf-schema#comment | "The endoplasmic reticulum (ER) consists of the nuclear envelope and a peripheral network of tubules and membrane sheets. The tubules are shaped by the curvature-stabilizing proteins reticulons and DP1/Yop1p, but how the sheets are formed is unclear. Here, we identify several sheet-enriched membrane proteins in the mammalian ER, including proteins that translocate and modify newly synthesized polypeptides, as well as coiled-coil membrane proteins that are highly upregulated in cells with proliferated ER sheets, all of which are localized by membrane-bound polysomes. These results indicate that sheets and tubules correspond to rough and smooth ER, respectively. One of the coiled-coil proteins, Climp63, serves as a "luminal ER spacer" and forms sheets when overexpressed. More universally, however, sheet formation appears to involve the reticulons and DP1/Yop1p, which localize to sheet edges and whose abundance determines the ratio of sheets to tubules. These proteins may generate sheets by stabilizing the high curvature of edges."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2010.11.007"xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Shibata Y."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Rapoport T.A."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Prinz W.A."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Kozlov M.M."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Shemesh T."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/author | "Palazzo A.F."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/pages | "774-788"xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/title | "Mechanisms determining the morphology of the peripheral ER."xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://purl.uniprot.org/core/volume | "143"xsd:string |
| http://purl.uniprot.org/citations/21111237 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21111237 |
| http://purl.uniprot.org/citations/21111237 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21111237 |
| http://purl.uniprot.org/uniprot/#_A7BI36-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_B3KSG1-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_A1A5C4-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_A1A5C5-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_B3KVX6-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_Q07065-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_Q32NB1-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_Q9P2E9-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |
| http://purl.uniprot.org/uniprot/#_Q6NWZ1-mappedCitation-21111237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21111237 |