http://purl.uniprot.org/citations/21134747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21134747 | http://www.w3.org/2000/01/rdf-schema#comment | "Herein we describe the synthesis and structure activity relationship of a new class of FXR agonists identified from a high-throughput screening campaign. Further optimization of the original hits led to molecules that were highly active in an LDL-receptor KO model for dyslipidemia. The most promising candidate is discussed in more detail."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bmcl.2010.11.039"xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Feng S."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Taylor S."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Rudolph M.G."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Martin R.E."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Kuhn B."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Blum D."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Grether U."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Gardes C."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Schuler F."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Richter H.G."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Chaput E."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Benson G.M."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Hartman P."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Plancher J.M."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/author | "Bleicher K.H."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/name | "Bioorg Med Chem Lett"xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/pages | "191-194"xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/title | "Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes."xsd:string |
http://purl.uniprot.org/citations/21134747 | http://purl.uniprot.org/core/volume | "21"xsd:string |
http://purl.uniprot.org/citations/21134747 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21134747 |
http://purl.uniprot.org/citations/21134747 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21134747 |