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http://purl.uniprot.org/citations/2113846http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2113846http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2113846http://www.w3.org/2000/01/rdf-schema#comment"1. Three pepsins were purified from the gastric mucosa of Atlantic cod (Gadus morhua). 2. The enzymes, called Pepsin I and Pepsin IIa and b, had isoelectric points 6.9, 4.0 and 4.1, respectively, and digested hemoglobin at a maximal rate at a pH of approximately 3. 3. They resembled bovine cathepsin D in being unable to digest the mammalian pepsin substrate N-acetyl-L-phenylalanyl-3,5-diiodo-L-tyrosine. 4. Specificity constants (kcat/Km) for the cod pepsins were lower than for porcine pepsin, and they expressed higher substrate affinity and physiological efficiency at pH 3.5 than at pH 2. 5. The cod pepsins are glycoproteins, and their amino acid composition resembles that of porcine cathepsin D more than that of porcine pepsin. 6. The N-terminal sequence of Atlantic cod pepsins is substantially different from that of porcine pepsin. This indicates a significant evolutionary gap between fish and mammalian pepsins."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.org/dc/terms/identifier"doi:10.1016/0305-0491(90)90382-4"xsd:string
http://purl.uniprot.org/citations/2113846http://purl.org/dc/terms/identifier"doi:10.1016/0305-0491(90)90382-4"xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Bjarnason J.B."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Bjarnason J.B."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Gildberg A."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Gildberg A."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Olsen R.L."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/author"Olsen R.L."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/name"Comp. Biochem. Physiol."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/name"Comp. Biochem. Physiol."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/pages"323-330"xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/pages"323-330"xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/title"Catalytic properties and chemical composition of pepsins from Atlantic cod (Gadus morhua)."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/title"Catalytic properties and chemical composition of pepsins from Atlantic cod (Gadus morhua)."xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/volume"96B"xsd:string
http://purl.uniprot.org/citations/2113846http://purl.uniprot.org/core/volume"96B"xsd:string
http://purl.uniprot.org/citations/2113846http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2113846
http://purl.uniprot.org/citations/2113846http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2113846
http://purl.uniprot.org/citations/2113846http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2113846
http://purl.uniprot.org/citations/2113846http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2113846