| http://purl.uniprot.org/citations/21156282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21156282 | http://www.w3.org/2000/01/rdf-schema#comment | "Diffuse large B cell lymphoma (DLBCL) comprises disease entities with distinct genetic profiles, including germinal center B cell (GCB)-like and activated B cell (ABC)-like DLBCLs. Major differences between these two subtypes include genetic aberrations leading to constitutive NF-κB activation and interference with terminal B cell differentiation through BLIMP1 inactivation, observed in ABC-but not GCB-DLBCL. Using conditional gain-of-function and/or loss-of-function mutagenesis in the mouse, we show that constitutive activation of the canonical NF-κB pathway cooperates with disruption of BLIMP1 in the development of a lymphoma that resembles human ABC-DLBCL. Our work suggests that both NF-κB signaling, as an oncogenic event, and BLIMP1, as a tumor suppressor, play causal roles in the pathogenesis of ABC-DLBCL."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ccr.2010.11.024"xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Sasaki Y."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Zhang B."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Tarakhovsky A."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Rajewsky K."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Schmidt-Supprian M."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Rodig S."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Kutok J."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Srinivasan L."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Seagal J."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Calado D.P."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/author | "Unitt C."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/name | "Cancer Cell"xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/pages | "580-589"xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/title | "Constitutive canonical NF-kappaB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma."xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/21156282 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21156282 |
| http://purl.uniprot.org/citations/21156282 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21156282 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JGK6-mappedCitation-21156282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21156282 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWR2-mappedCitation-21156282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21156282 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J0T4-mappedCitation-21156282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21156282 |
| http://purl.uniprot.org/uniprot/#_A0A075B5P4-mappedCitation-21156282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21156282 |