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http://purl.uniprot.org/citations/21164262 | http://www.w3.org/2000/01/rdf-schema#comment | "The disturbance of the hypothalamic-pituitary-adrenal axis characteristic of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) is likely to affect brain development, yet neuroanatomic work is only beginning. Fetal hyperandrogenemia in 46, XX 21-OHD leads to masculinized brain organization and, consequently, at later stages of development, to masculinized gender-related behavior and cognitive function, including, although relatively uncommonly, gender identity. Genital masculinization as well as its surgical treatment has implications for social stigmatization and sexual functioning. CAH-associated electrolyte crises in infancy and later may result in severe cognitive impairment. Psychiatric disorders are somewhat increased, especially in patients with severe degrees of CAH."xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.org/dc/terms/identifier | "doi:10.1159/000321225"xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/author | "Meyer-Bahlburg H.F.L."xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/name | "Endocr Dev"xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/pages | "88-95"xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/title | "Brain development and cognitive, psychosocial, and psychiatric functioning in classical 21-hydroxylase deficiency."xsd:string |
http://purl.uniprot.org/citations/21164262 | http://purl.uniprot.org/core/volume | "20"xsd:string |
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