| http://purl.uniprot.org/citations/21168411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21168411 | http://www.w3.org/2000/01/rdf-schema#comment | "Room temperature neutron diffraction data of the fully perdeuterated Toho-1 R274N/R276N double mutant β-lactamase in the apo form were used to visualize deuterium atoms within the active site of the enzyme. This perdeuterated neutron structure of the Toho-1 R274N/R276N reveals the clearest picture yet of the ground-state active site protonation states and the complete hydrogen-bonding network in a β-lactamase enzyme. The ground-state active site protonation states detailed in this neutron diffraction study are consistent with previous high-resolution X-ray studies that support the role of Glu166 as the general base during the acylation reaction in the class A β-lactamase reaction pathway."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.12.017"xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Chen Y."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Cooper J."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Coates L."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Weiss K.L."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Wang K.K."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Blakeley M.P."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/author | "Tomanicek S.J."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/pages | "364-368"xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/title | "The active site protonation states of perdeuterated Toho-1 beta-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation."xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://purl.uniprot.org/core/volume | "585"xsd:string |
| http://purl.uniprot.org/citations/21168411 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21168411 |
| http://purl.uniprot.org/citations/21168411 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21168411 |
| http://purl.uniprot.org/uniprot/#_Q47066-mappedCitation-21168411 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21168411 |
| http://purl.uniprot.org/uniprot/Q47066 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21168411 |