| http://purl.uniprot.org/citations/21174060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21174060 | http://www.w3.org/2000/01/rdf-schema#comment | "RC-RNase exerts anti-cancer effects on many tumors. However, the mechanisms by which RC-RNase induces cytotoxicity in different tumor cells are unclear. Currently, estrogen receptor (ER)-positive and negative breast tumors are treated with RC-RNase. Our data demonstrate that RC-RNase induces cell death on ER-positive but not on ER-negative breast tumors. This study also shows that down-regulation of ER and Bcl-2 is found on RC-RNase-treated ER-positive breast tumors. Additionally, Bcl-2 overxpression can prevent ER-positive breast tumors from cell death treated with RC-RNase. In summary, this study demonstrates that RC-RNase-induced cell death of ER-positive breast tumors is through regulation of ER and Bcl-2."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.org/dc/terms/identifier | "doi:10.3892/or.2010.1114"xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Chen Y.L."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Chen J.H."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Lee M.C."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Wang J.J."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Chen M.H."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Huang T.H."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Chou C.L."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Yu Y.L."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Kuo T.Y."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Tseng H.H."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/author | "Yiang G.T."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/name | "Oncol Rep"xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/pages | "849-853"xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/title | "RC-RNase-induced cell death in estrogen receptor positive breast tumors through down-regulation of Bcl-2 and estrogen receptor."xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/21174060 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21174060 |
| http://purl.uniprot.org/citations/21174060 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21174060 |
| http://purl.uniprot.org/uniprot/#_A0A125SXW0-mappedCitation-21174060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21174060 |
| http://purl.uniprot.org/uniprot/#_A0A125SXW1-mappedCitation-21174060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21174060 |
| http://purl.uniprot.org/uniprot/#_A0A1L4AQQ4-mappedCitation-21174060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21174060 |
| http://purl.uniprot.org/uniprot/#_P10415-mappedCitation-21174060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21174060 |