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http://purl.uniprot.org/citations/21179090http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21179090http://www.w3.org/2000/01/rdf-schema#comment"Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless, its genome still contains unannotated coding and non-coding genes, transcripts, exons and RNA editing sites. Full discovery and annotation are pre-requisites for understanding how the regulation of transcription, splicing and RNA editing directs the development of this complex organism. Here we used RNA-Seq, tiling microarrays and cDNA sequencing to explore the transcriptome in 30 distinct developmental stages. We identified 111,195 new elements, including thousands of genes, coding and non-coding transcripts, exons, splicing and editing events, and inferred protein isoforms that previously eluded discovery using established experimental, prediction and conservation-based approaches. These data substantially expand the number of known transcribed elements in the Drosophila genome and provide a high-resolution view of transcriptome dynamics throughout development."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.org/dc/terms/identifier"doi:10.1038/nature09715"xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Andrews J."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Brenner S.E."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Brent M.R."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Carlson J.W."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Celniker S.E."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Gingeras T.R."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Green R.E."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Jiang L."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Hoskins R.A."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Lin W."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Li R."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Perrimon N."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Zhang Y."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Yang L."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Wan K.H."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Zhang D."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Zou Y."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Brooks A.N."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Duff M.O."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Graveley B.R."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Dudoit S."xsd:string
http://purl.uniprot.org/citations/21179090http://purl.uniprot.org/core/author"Miller D."xsd:string