http://purl.uniprot.org/citations/21191402 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21191402 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21191402 | http://www.w3.org/2000/01/rdf-schema#comment | "Heritable skin diseases represent a broad spectrum of clinical manifestations due to mutations in ∼500 different genes. A number of model systems have been developed to advance our understanding of the pathomechanisms of genodermatoses. Zebrafish (Danio rerio), a freshwater vertebrate, has a well-characterized genome, the expression of which can be easily manipulated. The larvae develop rapidly, with all major organs having developed by 5-6 days post-fertilization, including the skin, consisting of the epidermis comprising two cell layers and separated from the dermal collagenous matrix by a basement membrane. This perspective highlights the morphological and ultrastructural features of zebrafish skin, in the context of cutaneous gene expression. These observations suggest that zebrafish provide a useful model system to study the molecular aspects of skin development, as well as the pathogenesis and treatment of select heritable skin diseases."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.org/dc/terms/identifier | "doi:10.1038/jid.2010.388"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Uitto J."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Uitto J."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Frank M."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Frank M."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Thisse B.V."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Thisse B.V."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Thisse C.I."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/author | "Thisse C.I."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/name | "J. Invest. Dermatol."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/name | "J Invest Dermatol"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/pages | "565-571"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/pages | "565-571"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/title | "Zebrafish: a model system to study heritable skin diseases."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/title | "Zebrafish: a model system to study heritable skin diseases."xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/volume | "131"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://purl.uniprot.org/core/volume | "131"xsd:string |
http://purl.uniprot.org/citations/21191402 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21191402 |