| http://purl.uniprot.org/citations/21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21195352 | http://www.w3.org/2000/01/rdf-schema#comment | "The gastrointestinal tract is emerging as a key regulator of appetite and metabolism, but daunting neuroanatomical complexity has hampered identification of the relevant signals. Invertebrate models could provide a simple and genetically amenable alternative, but their autonomic nervous system and its visceral functions remain largely unexplored. Here we develop a quantitative method based on defecation behavior to uncover a central role for the Drosophila intestine in the regulation of nutrient intake, fluid, and ion balance. We then identify a key homeostatic role for autonomic neurons and hormones, including a brain-gut circuit of insulin-producing neurons modulating appetite, a vasopressin-like system essential for fluid homeostasis, and enteric neurons mediating sex peptide-induced changes in intestinal physiology. These conserved mechanisms of visceral control, analogous to those found in the enteric nervous system and hypothalamic/pituitary axis, enable the study of autonomic control in a model organism that has proved instrumental in understanding sensory and motor systems."xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cmet.2010.12.010"xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/author | "Miguel-Aliaga I."xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/author | "Bailey A.P."xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/author | "Cognigni P."xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/name | "Cell Metab"xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/pages | "92-104"xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/title | "Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis."xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/21195352 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21195352 |
| http://purl.uniprot.org/citations/21195352 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KF38-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0C4DHD8-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6Q9-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6R4-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6R8-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6S2-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6V0-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6Y9-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6Z3-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K6Z8-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_P15278-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7T4-mappedCitation-21195352 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21195352 |