| http://purl.uniprot.org/citations/21199657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21199657 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21199657 | http://www.w3.org/2000/01/rdf-schema#comment | "Neurotensin, a tridecapeptide, is distributed in a wide range of tissues and exhibits multiple functions through its receptors. Hitherto molecular characterization of the neurotensin receptor has been reported in mammalian, amphibian, and fish species but not in avian species. In this study, we cloned the cDNA encoding chicken neurotensin receptor from the duodenum and characterized its primary structure, biological activity and distribution in the gastrointestinal tract. The cDNA encoded a protein consisting of 399 amino acids that had significant overall sequence homology to other vertebrate neurotensin receptor 1 with higher extent in the seven transmembrane domains. Chicken neurotensin increased intracellular Ca(2+) concentrations in human embryonic kidney 293 cells transiently expressing the chicken neurotensin receptor 1. Real-time PCR analysis showed that chicken neurotensin receptor 1 mRNA is expressed throughout the gastrointestinal tract with markedly higher level in the colon/rectum. These results indicate that the chicken neurotensin receptor 1 is involved in gastrointestinal functions through an intracellular signaling pathway accompanied by an increase in Ca(2+) levels."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygcen.2010.12.021"xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygcen.2010.12.021"xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Sudo H."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Sudo H."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Tanaka M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Tanaka M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Yamamoto I."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Yamamoto I."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Kaiya H."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Kaiya H."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Miyazato M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Miyazato M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Nakao N."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Nakao N."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Tsushima N."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Tsushima N."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Numao M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/author | "Numao M."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/name | "Gen. Comp. Endocrinol."xsd:string |
| http://purl.uniprot.org/citations/21199657 | http://purl.uniprot.org/core/name | "Gen Comp Endocrinol"xsd:string |