| http://purl.uniprot.org/citations/21203937 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21203937 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21203937 | http://www.w3.org/2000/01/rdf-schema#comment | "RING finger protein 152 (RNF152) is a novel RING finger protein and has not been well characterized. We report here that RNF152 is a canonical RING finger protein and has E3 ligase activity. It is polyubiqitinated partly through Lys-48-linked ubiquitin chains in vivo and this phenomenon is dependent on its RING finger domain and transmembrane domain. RNF152 is localized in lysosomes and co-localized with LAMP3, a lysosome marker. Moreover, over-expression of RNF152 in Hela cells induces apoptosis. These results suggest that RNF152 is a lysosome localized E3 ligase with pro-apoptotic activities. It is the first E3 ligase identified so far that is involved in lysosome-related apoptosis."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.org/dc/terms/identifier | "doi:10.1007/s13238-010-0083-1"xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.org/dc/terms/identifier | "doi:10.1007/s13238-010-0083-1"xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Tang H."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Tang H."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Zhang S."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Zhang S."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Zheng J."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Zheng J."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Wu W."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Wu W."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Suo T."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/author | "Suo T."xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/name | "Protein Cell"xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/name | "Protein Cell"xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/pages | "656-663"xsd:string |
| http://purl.uniprot.org/citations/21203937 | http://purl.uniprot.org/core/pages | "656-663"xsd:string |