| http://purl.uniprot.org/citations/21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21221603 | http://www.w3.org/2000/01/rdf-schema#comment | "The importance of the interaction between natural killer (NK) cells and dendritic cells (DCs) in the expansion of antiviral and antitumor immune responses is well documented; however, limited information on NK/DC interaction during atherosclerosis is available. Inflammation plays an important role in the development of atherosclerosis, and oxidized low-density lipoprotein (ox-LDL) is believed to play a critical role in the development and progression of atherosclerosis. In this study, we developed a NK/DC coculture system to examine the role of ox-LDL in modulating the interaction of mice NK cells and DCs. Fresh NK cells were cocultured with DCs in the absence or presence of ox-LDL. We examined the cytokines released during the interaction. This report provides the first evidence of an enhancement effect by ox-LDL on the NK/DC crosstalk. Notably, we found that ox-LDL significantly promoted the interaction of NK cells and DCs via CD48-2B4 contact-dependent mechanisms. These findings highlight the importance of NK/DCs crosstalk in atherosclerosis and provide new information about the possible mechanisms of atherosclerosis."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00380-010-0102-4"xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Li S."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Dong K."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Zhu W.G."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Gu S.L."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Zhu J.H."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Fan F.Y."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/author | "Ge J.H."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/name | "Heart Vessels"xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/pages | "637-645"xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/title | "Ox-LDL can enhance the interaction of mice natural killer cells and dendritic cells via the CD48-2B4 pathway."xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://purl.uniprot.org/core/volume | "26"xsd:string |
| http://purl.uniprot.org/citations/21221603 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21221603 |
| http://purl.uniprot.org/citations/21221603 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21221603 |
| http://purl.uniprot.org/uniprot/#_Q07763-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q18PH8-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_P18181-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q3S4B1-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q3S4B2-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q3TAZ6-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q3TBI0-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |
| http://purl.uniprot.org/uniprot/#_Q3TDI8-mappedCitation-21221603 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21221603 |