| http://purl.uniprot.org/citations/2123831 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2123831 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2123831 | http://www.w3.org/2000/01/rdf-schema#comment | "The soluble hemagglutinin/protease (HA/protease) produced by Vibrio cholerae and the elastase of Pseudomonas aeruginosa are both zinc/calcium-dependent proteases. In the present study the two enzymes are compared immunologically and functionally. The N-terminal amino acid sequences of the proteins had 65% identity within the first 20 amino acids. Polyclonal antisera against each purified protein recognized the enzyme of the other species in enzyme-linked immunosorbent assay, checkerboard immunoblot, and Western blot analyses and inhibited the protease activity of both enzymes in milk and elastin agars. Like the HA/protease, the elastase hemagglutinated "responder" but not "nonresponder" chicken erythrocytes, degraded ovomucin, lactoferrin, and fibronectin, and nicked the A subunit of the cholera toxin-related heat-labile enterotoxin from Escherichia coli. Whereas none of the three proteases tested (elastase, HA/protease, or pronase E) had any obvious effect in ileal loop tests in rabbits at doses up to 50 micrograms, all three produced some detectable skin reactions at a dose of 0.1 micrograms and necrosis at a higher dose (i.e., 5 micrograms). We conclude that the V. cholerae HA/protease and the P. aeruginosa elastase are structurally, functionally, and immunologically related."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.org/dc/terms/identifier | "doi:10.1128/iai.58.12.4011-4015.1990"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.org/dc/terms/identifier | "doi:10.1128/iai.58.12.4011-4015.1990"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/author | "Finkelstein R.A."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/author | "Finkelstein R.A."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/author | "Haese C.C."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/author | "Haese C.C."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/name | "Infect. Immun."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/name | "Infect. Immun."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/pages | "4011-4015"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/pages | "4011-4015"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/title | "Comparison of the Vibrio cholerae hemagglutinin/protease and the Pseudomonas aeruginosa elastase."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/title | "Comparison of the Vibrio cholerae hemagglutinin/protease and the Pseudomonas aeruginosa elastase."xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/2123831 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2123831 |
| http://purl.uniprot.org/citations/2123831 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2123831 |
| http://purl.uniprot.org/citations/2123831 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2123831 |
| http://purl.uniprot.org/citations/2123831 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2123831 |
| http://purl.uniprot.org/uniprot/P24153 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2123831 |
| http://purl.uniprot.org/uniprot/P14756 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2123831 |