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http://purl.uniprot.org/citations/21256590 | http://www.w3.org/2000/01/rdf-schema#comment | "Overexpression of the Wilms' tumor gene 1 (WT1) was observed in most leukemia cells. In addition to four major isoforms of WT1, an N-terminally truncated isoforms (sWT1) has been identified. We separately quantified the transcript levels of sWT1 and full-length WT1 (fWT1) in 237 patients with acute myeloid leukemia (AML). sWT1 expression was observed in 45 of 237 (19.0%) AML patients, particularly in acute promyelocytic leukemia (59.3%). Although sWT1 expression was not associated with other genetic mutations and prognosis, fWT1 expression level in sWT1-expressing AML was significantly higher than that in un-expressing AML. These results suggested the possible cooperation of sWT1 and fWT1 in the pathophysiology of AML, while further analysis is required."xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.leukres.2011.01.002"xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/author | "Ishikawa Y."xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/author | "Kiyoi H."xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/author | "Naoe T."xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/name | "Leuk Res"xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/pages | "685-688"xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/title | "Prevalence and clinical characteristics of N-terminally truncated WT1 expression in acute myeloid leukemia."xsd:string |
http://purl.uniprot.org/citations/21256590 | http://purl.uniprot.org/core/volume | "35"xsd:string |
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