DESCRIBE <http://purl.uniprot.org/citations/21349256>

Subject	Predicate	Object
http://purl.uniprot.org/citations/21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21349256	http://www.w3.org/2000/01/rdf-schema#comment	" Objectives There are evidences that immuno-inflammatory mechanisms and apoptosis may play a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). It is known that Granzyme A (GzmA) and granzyme B (GzmB) are implicated in these mechanisms. The aim of the study was to investigate serum GzmA and GzmB levels in patients with ALS. Design and methods The study included 30 patients with ALS and 30 patients from the control group. Serum GzmA and GzmB levels were measured using the enzyme-linked immunosorbent method. Results The study showed that GzmA and GzmB levels are significantly increased in serum of patients with ALS when compared to the control group (p<0.05). There was a significant correlation of serum GzmB levels with severity of clinical state of ALS patients (p<0.05). Conclusion The results indicate that GzmA and GzmB are implicated in mechanisms of neurodegeneration in ALS."xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.org/dc/terms/identifier	"doi:10.1016/j.clinbiochem.2011.02.006"xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/author	"Ilzecka J."xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/date	"2011"xsd:gYear
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/name	"Clin Biochem"xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/pages	"650-653"xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/title	"Granzymes A and B levels in serum of patients with amyotrophic lateral sclerosis."xsd:string
http://purl.uniprot.org/citations/21349256	http://purl.uniprot.org/core/volume	"44"xsd:string
http://purl.uniprot.org/citations/21349256	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/21349256
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http://purl.uniprot.org/uniprot/#_J3KQ52-mappedCitation-21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21349256
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http://purl.uniprot.org/uniprot/#_P12544-mappedCitation-21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/#_Q6XGZ2-mappedCitation-21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/#_Q6XGZ3-mappedCitation-21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/#_Q6XGZ4-mappedCitation-21349256	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/P10144	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21349256
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http://purl.uniprot.org/uniprot/Q6XGZ4	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/Q67BC3	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21349256
http://purl.uniprot.org/uniprot/P12544	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21349256
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