| http://purl.uniprot.org/citations/21359250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21359250 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveIL-10 is a cytokine that plays a complex role in the control of immune responses. A case-control study was conducted to investigate the expression pattern of IL-10 in both serum and the whole unstimulated saliva from ethnic Chinese patients with oral lichen planus.Method and materialsSeventy-nine Chinese patients with oral lichen planus were recruited for this study, and 41 healthy volunteers served as a control group. The levels of IL-10 and IFN-g in the serum and saliva were detected using enzyme-linked immunosorbent assay (ELISA). The IFN-g/IL-10 ratio was calculated by direct counting.ResultsThe results demonstrated an expression profile of high IL-10 level and low IFN-g level and IFN-g/IL-10 ratio in both serum and saliva from oral lichen planus patients, compared to the controls. Saliva levels of IL-10 and IFN-g were positively correlated to their serum partners. No significant difference was found among subtypes of oral lichen planus.ConclusionElevation of IL-10 level might be involved in the pathogenesis of oral lichen planus, and saliva might be a substitute for serum to reflect the disease-related cytokine production in oral lichen planus patients."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Chen Q."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Liu W."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Wang Z."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Zhou Y."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Wu R."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Zeng X."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/author | "Dan H."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/name | "Quintessence Int"xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/pages | "157-163"xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/title | "Elevated IL-10 concentrations in serum and saliva from patients with oral lichen planus."xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://purl.uniprot.org/core/volume | "42"xsd:string |
| http://purl.uniprot.org/citations/21359250 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21359250 |
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