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| http://purl.uniprot.org/citations/21396404 | http://www.w3.org/2000/01/rdf-schema#comment | "The forkhead box O transcription factors convert a variety of external stimuli, including growth factors, nutrients, and oxidative stress, into diverse biological responses through modulation of specific gene expression. Forkhead box O regulation is principally achieved by two distinct mechanisms: post-translational modifications and protein-protein interactions. Among several modifications of forkhead box O factors, we focus on reversible acetylation, describing past research and current advances. In the latter part of this review, we also provide an overview of forkhead box O-binding partners that control the transcriptional activity of forkhead box O factors. These two layers of regulation mostly overlap and thereby enable a more precise fine-tuning of forkhead box O functions involved in metabolism, longevity, and tumor suppression. This article is part of a Special Issue entitled: PI3K-AKT-FoxO axis in cancer and aging."xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbamcr.2011.03.001"xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/author | "Daitoku H."xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/author | "Fukamizu A."xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/author | "Sakamaki J."xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/pages | "1954-1960"xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/title | "Regulation of FoxO transcription factors by acetylation and protein-protein interactions."xsd:string |
| http://purl.uniprot.org/citations/21396404 | http://purl.uniprot.org/core/volume | "1813"xsd:string |
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