| http://purl.uniprot.org/citations/21399669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21399669 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA-G molecules are HLA class Ib antigens characterized by tolerogenic and immunoinhibitory functions. The HLA-G 14-bp insertion/deletion (ins/del) polymorphism controls protein expression and seems to be implicated in both MTX treatment response and SCT outcome. The aim of our study is to evaluate the role of HLA-G 14 bp polymorphism in subjects affected by hematological malignancies undergoing allo-SCT and receiving MTX therapy for GvHD prophylaxis. We performed a retrospective analysis of HLA-G 14 bp polymorphism using a specific PCR in 47 recipients and in their respective donors, and evaluated the correlation with the incidence of aGvHD, OS and disease-free survival (DFS) after allo-SCT. We did not observe any correlation between this polymorphism and the risk of aGvHD occurrence. On the contrary, we found that the recipients with a 14 bp ins/14 bp ins genotype were characterized by a lower OS and DFS in univariate and multivariate analysis (OS=OR: 3.235; DFS=OR: 3.302). These data indicate a role for recipient HLA-G 14 bp polymorphism in allo-SCT immunotolerance status and follow-up."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.org/dc/terms/identifier | "doi:10.1038/bmt.2011.40"xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Leone G."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Rizzo R."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Bellesi S."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Marietti S."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Sica S."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Baricordi O.R."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Chiusolo P."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Stignani M."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "De Ritis D."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Giammarco S."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Metafuni E."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/author | "Piccirillo N."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/name | "Bone Marrow Transplant"xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/pages | "120-124"xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/title | "The role of HLA--G 14-bp polymorphism in allo-HSCT after short-term course MTX for GvHD prophylaxis."xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://purl.uniprot.org/core/volume | "47"xsd:string |
| http://purl.uniprot.org/citations/21399669 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21399669 |
| http://purl.uniprot.org/citations/21399669 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21399669 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-21399669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21399669 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-21399669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21399669 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-21399669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21399669 |