| http://purl.uniprot.org/citations/21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21406181 | http://www.w3.org/2000/01/rdf-schema#comment | "The RGD motif on the extracellular matrix or cell surface, together with its integrin receptors, constitutes a major recognition system for cell adhesion. There are several erythrocyte major membrane skeletal proteins, e.g., α spectrin, ankyrin, and protein 4.2, that bear an RGD motif. However, it is not known whether the RGD/integrin recognition system is utilized in the erythrocyte-macrophage adhesion during erythrophagocytosis. Here we report that the RGD motif of ankyrin, but not others, is recognized by the α(v)β(3) integrin receptor. In addition, the RGD motif of ankyrin, a peripheral membrane protein, can be externalized onto the cell surface when erythrocytes are incubated with calcium and sheared both at physiological levels. Furthermore, the erythrocyte-macrophage adhesion can be specifically inhibited by ankyrin and/or α(v)β(3). Thus, externalization of ankyrin followed by RGD/integrin recognition may be a novel mechanism by which erythrocytes adhere to macrophages preceding phagocytosis."xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2011.03.035"xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/author | "Peng W."xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/author | "Sung L.A."xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/pages | "466-471"xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/title | "RGD-containing ankyrin externalized onto the cell surface triggers alphaVbeta3 integrin-mediated erythrophagocytosis."xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://purl.uniprot.org/core/volume | "407"xsd:string |
| http://purl.uniprot.org/citations/21406181 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21406181 |
| http://purl.uniprot.org/citations/21406181 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21406181 |
| http://purl.uniprot.org/uniprot/#_A0A0F7IQ06-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_D3Z5M4-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J1N7-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A0A5F8MQC3-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A2AKI5-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A3KGU5-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A3KGU7-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A3KGU9-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_B2RXX6-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_A3KGU4-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_B7ZCI9-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_B9EKJ1-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |
| http://purl.uniprot.org/uniprot/#_E9QNT8-mappedCitation-21406181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21406181 |