DESCRIBE <http://purl.uniprot.org/citations/21448168>

Subject	Predicate	Object
http://purl.uniprot.org/citations/21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21448168	http://www.w3.org/2000/01/rdf-schema#comment	" Purpose Tumour epithelial vimentin expression is a marker of mesenchymal differentiation and may be a useful marker of carcinomas with more aggressive behaviour. The aim of this study was to determine the extent and prognostic significance of vimentin expression in pancreatic ductal adenocarcinomas. Methods Vimentin expression was detected by immunohistochemistry on tissue microarrays of surgically resected pancreatic ductal adenocarcinomas from 387 patients. The percentage of vimentin-immunolabelled neoplastic cells was correlated with outcome and with clinico-pathological factors using the Kaplan-Meier method and Cox multivariate survival models. Results In all, 45% of primary pancreatic adenocarcinomas contained neoplastic cells that expressed vimentin, and in 27.5% of the cancers >10% of cells expressed vimentin. Vimentin expression was correlated with poor histological differentiation. By both uni- and multivariate survival analysis, neoplastic vimentin expression (P<0.01, HR 1.52, 95% confidence interval 1.14-2.04) was an indicator of a shorter postsurgical survival independent of other clinico-pathological variables. Conclusion The presence of vimentin-expressing tumour epithelial cells in surgically resected pancreatic adenocarcinomas independently predicted a shorter postsurgical survival."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.org/dc/terms/identifier	"doi:10.1038/bjc.2011.93"xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Walter K."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Goggins M."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Hong S.M."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Wolfgang C."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Hruban R."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/author	"Handra-Luca A."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/date	"2011"xsd:gYear
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/name	"Br J Cancer"xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/pages	"1296-1302"xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/title	"Tumour epithelial vimentin expression and outcome of pancreatic ductal adenocarcinomas."xsd:string
http://purl.uniprot.org/citations/21448168	http://purl.uniprot.org/core/volume	"104"xsd:string
http://purl.uniprot.org/citations/21448168	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/21448168
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http://purl.uniprot.org/uniprot/#_A0A0S2Z4T0-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/#_B0YJC4-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/#_B0YJC5-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
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http://purl.uniprot.org/uniprot/#_P08670-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/#_Q53HU8-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/#_V9HWE1-mappedCitation-21448168	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/B3KRK8	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21448168
http://purl.uniprot.org/uniprot/P08670	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/21448168