| http://purl.uniprot.org/citations/21460847 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21460847 | http://www.w3.org/2000/01/rdf-schema#comment | "The immunoregulatory cytokine interleukin 10 (IL-10) is expressed mainly by T helper type 2 (T(H)2) cells but also by T(H)1 cells during chronic infection. Here we observed plasticity in the expression of IL-10 and IL-13 after chronic T(H)1 stimulation; furthermore, the expression of Il10 and Il13 was regulated by the transcription factor E4BP4. Chronically stimulated E4BP4-deficient (Nfil3(-/-); called 'E4bp4(-/-)' here) T(H)1 cells, regulatory T cells (T(reg) cells) and natural killer T cells (NKT cells) had attenuated expression of IL-10 and IL-13. Enforced expression of E4bp4 initiated the production of IL-10 and IL-13 by conventional T(H)1 cells. E4bp4(-/-) T(H)2 cells showed impairment of IL-10 production with no effect on IL-13. Our results indicate that E4BP4 has multiple functions in controlling the plasticity of IL-13 in T(H)1 cells and IL-10 in T(H)1 cells, T(H)2 cells, T(reg) cells and NKT cells."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni.2020"xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Inoue H."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Kitamura H."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Kubo M."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Matsumoto K."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Taniguchi M."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Hori S."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Motomura Y."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Matsunaga Y."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Hijikata A."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Atarashi K."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/author | "Watarai H."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/pages | "450-459"xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/title | "The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells."xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/21460847 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21460847 |
| http://purl.uniprot.org/citations/21460847 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21460847 |
| http://purl.uniprot.org/uniprot/P06332#attribution-B916D148D7AE111506B985A5C259062D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/21460847 |
| http://purl.uniprot.org/uniprot/P37217#attribution-B916D148D7AE111506B985A5C259062D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/21460847 |
| http://purl.uniprot.org/uniprot/P15379#attribution-B916D148D7AE111506B985A5C259062D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/21460847 |