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http://purl.uniprot.org/citations/21468611http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21468611http://www.w3.org/2000/01/rdf-schema#comment"Hemoglobin (Hb) Ottawa [α15 (A13) Gly→Arg], also known as Hb Siam, was first described in an 82-year-old Canadian in 1974. The same year, a second case was reported in a 28-year-old Chinese male living in Thailand. A third case was found in 1986 in a Chinese female living in the Hubei province of China. Since then, there have been no reports of Hb Ottawa in mainland China in the English literature. Hb Ottawa results from a GGT→CGT mutation in codon 15 of the α1 or α2-globin gene. Hb Ottawa carriers do not present any clinical symptoms or hematological changes, and are often diagnosed during a health examination and thalassemia screening. In a hemoglobin survey of 9745 students in Chaozhou, Guangdong, China, we identified four cases of Hb Ottawa in a thalassemia screening by Hb electrophoresis, and confirmed it to be the result of a GGT→CGT mutation in codon 15 of the α2-globin gene by DNA sequence analysis."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.org/dc/terms/identifier"doi:10.3892/mmr.2011.467"xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Huang Y."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Lin M."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Lin C.P."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Wu J.R."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Zheng L.H."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/author"Yang L.Y."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/name"Mol Med Rep"xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/pages"581-583"xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/title"Molecular and clinical characteristics of hemoglobin Ottawa detected in a Chinese population."xsd:string
http://purl.uniprot.org/citations/21468611http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/21468611http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21468611
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http://purl.uniprot.org/uniprot/#_U6A216-mappedCitation-21468611http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21468611