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http://purl.uniprot.org/citations/21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21479242http://www.w3.org/2000/01/rdf-schema#comment"SNARE-mediated membrane fusion is a pivotal event for a wide-variety of biological processes. SNAP-25, a neuron-specific SNARE protein, has been well-characterized and mouse embryos lacking Snap25 are viable. However, the phenotype of mice lacking SNAP-23, the ubiquitously expressed SNAP-25 homolog, remains unknown. To reveal the importance of SNAP-23 function in mouse development, we generated Snap23-null mice by homologous recombination. We were unable to obtain newborn SNAP-23-deficient mice, and analysis of pre-implantation embryos from Snap23(Δ/wt) matings revealed that Snap23-null blastocysts were dying prior to implantation at embryonic day E3.5. Thus these data reveal a critical role for SNAP-23 during embryogenesis."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0018444"xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Tessarollo L."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Roche K.W."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Suh Y.H."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Roche P.A."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Mackem S."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Weih K.A."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/author"Yoshimoto-Furusawa A."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/pages"e18444"xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/title"Deletion of SNAP-23 results in pre-implantation embryonic lethality in mice."xsd:string
http://purl.uniprot.org/citations/21479242http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/21479242http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21479242
http://purl.uniprot.org/citations/21479242http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21479242
http://purl.uniprot.org/uniprot/#_A2AKH4-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/#_B0R029-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/#_B0R030-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/#_E9Q8A1-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/#_O09044-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/#_Q9D3L3-mappedCitation-21479242http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/E9Q8A1http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21479242
http://purl.uniprot.org/uniprot/B0R030http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21479242