| http://purl.uniprot.org/citations/21481790 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21481790 | http://www.w3.org/2000/01/rdf-schema#comment | "To identify oncogenic pathways in T cell acute lymphoblastic leukemia (T-ALL), we combined expression profiling of 117 pediatric patient samples and detailed molecular-cytogenetic analyses including the Chromosome Conformation Capture on Chip (4C) method. Two T-ALL subtypes were identified that lacked rearrangements of known oncogenes. One subtype associated with cortical arrest, expression of cell cycle genes, and ectopic NKX2-1 or NKX2-2 expression for which rearrangements were identified. The second subtype associated with immature T cell development and high expression of the MEF2C transcription factor as consequence of rearrangements of MEF2C, transcription factors that target MEF2C, or MEF2C-associated cofactors. We propose NKX2-1, NKX2-2, and MEF2C as T-ALL oncogenes that are activated by various rearrangements."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ccr.2011.02.008"xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Ferrando A.A."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Sigaux F."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Kooi C."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Soulier J."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Klous P."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "de Laat W."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Beverloo H.B."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Pieters R."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Meijerink J.P."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Stubbs A."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Pike-Overzet K."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Langerak A.W."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Staal F.J."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Verhaaf B."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Horstmann M."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Cayuela J.M."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Buijs-Gladdines J."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Homminga I."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "de Haas V."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "van Vlierberghe P."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Verstegen M."xsd:string |
| http://purl.uniprot.org/citations/21481790 | http://purl.uniprot.org/core/author | "Vuerhard M."xsd:string |