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| http://purl.uniprot.org/citations/21482524 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate possible factors up-regulating the expression of UTROPHIN, potential regulatory elements in the promoter of the human UTROPHIN was predicted by P-match software and verified by EMSA and ChIP. The mechanism of EN1 regulation of the human UTROPHIN expression was evaluated by RNA interference and real-time PCR analyses. Two potential EN1 binding sites in UTROPHIN promoter region were predicted by P-Match software but only the second site was verified to interact directly with EN1 by EMSA and ChIP. The results from RNA interference and real-time PCR showed that the mRNA level of UTROPHIN increased in HeLa cells after EN1 was knockdowned by siRNA. It indicated that EN1 might be a negative regulatory factor for UTROPHIN. Our study suggested that UTROPHIN might be a new target for DMD therapy."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.org/dc/terms/identifier | "doi:10.3724/sp.j.1005.2011.00347"xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Wang Z.D."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Lin C.K."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Jin C.L."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Cui W.T."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/author | "Cao D.H."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/name | "Yi Chuan"xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/pages | "347-352"xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/title | "[The regulation of UTROPHIN expression by EN1]."xsd:string |
| http://purl.uniprot.org/citations/21482524 | http://purl.uniprot.org/core/volume | "33"xsd:string |
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