| http://purl.uniprot.org/citations/2155780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2155780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2155780 | http://www.w3.org/2000/01/rdf-schema#comment | "Two cDNAs encoding variants (alpha 1 and alpha 2) of the strychnine binding subunit of the inhibitory glycine receptor (GlyR) were isolated from a human fetal brain cDNA library. The predicted amino acid sequences exhibit approximately 99% and approximately 76% identity to the previously characterized rat 48 kd polypeptide. Heterologous expression of the human alpha 1 and alpha 2 subunits in Xenopus oocytes resulted in the formation of glycine-gated strychnine-sensitive chloride channels, indicating that both polypeptides can form functional GlyRs. Using a panel of rodent-human hybrid cell lines, the gene encoding alpha 2 was mapped to the short arm (Xp21.2-p22.1) of the human X chromosome. In contrast, the alpha 1 subunit gene is autosomally located. These data indicate molecular heterogeneity of the human GlyR at the level of alpha subunit genes."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1990.tb08172.x"xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1990.tb08172.x"xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Betz H."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Betz H."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Seeburg P.H."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Seeburg P.H."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Schofield P.R."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Schofield P.R."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Mohandas T.K."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Mohandas T.K."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Siddique T."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Siddique T."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Becker C.-M."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Becker C.-M."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Grenningloh G."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Grenningloh G."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Schmieden V."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/author | "Schmieden V."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/2155780 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |