| http://purl.uniprot.org/citations/21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21601984 | http://www.w3.org/2000/01/rdf-schema#comment | "Inactive heterozygous aldehyde dehydrogenase-2 (ALDH2(*)1/(*)2) and less-active alcohol dehydrogenase-1B (ADH1B(*)1/(*)1) increase the risk of esophageal cancer in East Asian drinkers, and esophageal cancer multiplicity is strongly associated with ALDH2(*)1/(*)2. p53 alterations are key molecular events in multifocal carcinogenesis in the esophagus. We studied 260 esophageal-cancer free Japanese alcoholics with esophageal dysplasia diagnosed by biopsy of distinct iodine-unstained lesions (DIULs) ≥5mm. The degree of p53 protein accumulation was positively associated with the degree of atypia (p<0.0001) and size (p=0.040) of DIULs and with the presence of multiple DIULs (p=0.070), but not with ALDH2(*)1/(*)2 or ADH1B(*)1/(*)1."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.canlet.2011.04.020"xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Maruyama K."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Yokoyama A."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Matsui T."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Omori T."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Yokoyama T."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/author | "Mizukami T."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/name | "Cancer Lett"xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/pages | "112-117"xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/title | "p53 protein accumulation, iodine-unstained lesions, and alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 genotypes in Japanese alcoholic men with esophageal dysplasia."xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://purl.uniprot.org/core/volume | "308"xsd:string |
| http://purl.uniprot.org/citations/21601984 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21601984 |
| http://purl.uniprot.org/citations/21601984 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A0M4B4Y9-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A087WXZ1-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A0C4KX50-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A0C4L134-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A087X1Q1-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A218MJE5-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A087WT22-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |
| http://purl.uniprot.org/uniprot/#_A0A0A0U7X4-mappedCitation-21601984 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21601984 |