| http://purl.uniprot.org/citations/21626213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21626213 | http://www.w3.org/2000/01/rdf-schema#comment | "In order to enhance the structure determination process of macromolecular assemblies by NMR, we have implemented long-range pseudocontact shift (PCS) restraints into the data-driven protein docking package HADDOCK. We demonstrate the efficiency of the method on a synthetic, yet realistic case based on the lanthanide-labeled N-terminal ε domain of the E. coli DNA polymerase III (ε186) in complex with the HOT domain. Docking from the bound form of the two partners is swiftly executed (interface RMSDs < 1 Å) even with addition of very large amount of noise, while the conformational changes of the free form still present some challenges (interface RMSDs in a 3.1-3.9 Å range for the ten lowest energy complexes). Finally, using exclusively PCS as experimental information, we determine the structure of ε186 in complex with the HOT-homologue θ subunit of the E. coli DNA polymerase III."xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10858-011-9514-4"xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/author | "Bonvin A.M."xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/author | "Schmitz C."xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/name | "J Biomol NMR"xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/pages | "263-266"xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/title | "Protein-protein HADDocking using exclusively pseudocontact shifts."xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://purl.uniprot.org/core/volume | "50"xsd:string |
| http://purl.uniprot.org/citations/21626213 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21626213 |
| http://purl.uniprot.org/citations/21626213 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21626213 |
| http://purl.uniprot.org/uniprot/#_P03007-mappedCitation-21626213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21626213 |
| http://purl.uniprot.org/uniprot/#_P0ABS8-mappedCitation-21626213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21626213 |
| http://purl.uniprot.org/uniprot/P0ABS8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21626213 |
| http://purl.uniprot.org/uniprot/P03007 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21626213 |