| http://purl.uniprot.org/citations/21635204 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21635204 | http://www.w3.org/2000/01/rdf-schema#comment | "The relationship between telomere length (TL) and predisposition to myelodysplastic syndromes (MDS) remains unclear. We compared peripheral blood leukocyte (PBL) TL among cases of histologically confirmed MDS (n = 65) who were treatment-naive with no prior cancer history to age-matched controls (n = 63). Relative TL was measured in PBLs and saliva by quantitative polymerase chain reaction (PCR) and in CD15+ and CD19+ cells by flow cytometry-fluorescence in situ hybridization (flow-FISH). Human telomerase reverse transcriptase gene (hTERT) mutations were assessed by PCR. After adjustment for age and sex, relative TLs were reduced in PBLs (p = 0.02), CD15+ (p = 0.01), CD19+ (p = 0.25), and saliva (p = 0.13) in MDS cases versus controls, although only the PBL and CD15+ results were statistically significant. Among MDS cases, CD15+ and CD19+ cell TLs were positively correlated (p = 0.03). PBL TL was reduced among those occupationally exposed to paints and pesticides, but was not associated with hTERT genotype. Future studies are needed to further investigate constitutional telomere attrition as a possible predisposing factor for MDS."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.org/dc/terms/identifier | "doi:10.3109/10428194.2011.568648"xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Lee J.H."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Park H."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Guerrier M."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Park J.Y."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "List A.F."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Epling-Burnette P.K."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Cole A.L."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Rollison D.E."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Painter J.S."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Fulp W."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Jonathan K."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Komrokji R."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Lancet J."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/author | "Melendez-Santiago J."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/name | "Leuk Lymphoma"xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/pages | "1528-1536"xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/title | "Telomere length in myelodysplastic syndromes."xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/21635204 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21635204 |
| http://purl.uniprot.org/citations/21635204 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21635204 |
| http://purl.uniprot.org/uniprot/#_P15391-mappedCitation-21635204 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21635204 |