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http://purl.uniprot.org/citations/21636910http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21636910http://www.w3.org/2000/01/rdf-schema#comment"Treponema denticola is a primary etiological agent of periodontal disease. T. denticola evades complement-mediated killing by binding to the host's factor H (FH), a negative regulator of the alternative complement pathway. The T. denticola FH-binding protein has been identified and designated as factor H-binding protein B (FhbB). Crystals of recombinant FhbB were obtained by the hanging-drop vapor-diffusion method using sodium citrate and 0.2 M sodium thiocyanate. FhbB crystals diffracted to 1.8 Å resolution and belonged to space group P4(3)2(1)2 or P4(1)2(1)2, with unit-cell parameters a = b = 46.76, c = 167.68 Å. Two FhbB molecules per asymmetric unit gave a Matthews coefficient of 2.2 Å(3) Da(-1) and a solvent content of 44%. FhbB is the smallest bacterially produced FH-binding protein identified to date. Determination of its structure will provide unique insight into the minimal structural determinants required for FH binding."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.org/dc/terms/identifier"doi:10.1107/s1744309111011298"xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/author"Marconi R.T."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/author"Bell J.K."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/author"McDowell J.V."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/author"Miller D.P."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/name"Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/pages"678-681"xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/title"Crystallization of the factor H-binding protein, FhbB, from the periopathogen Treponema denticola."xsd:string
http://purl.uniprot.org/citations/21636910http://purl.uniprot.org/core/volume"67"xsd:string
http://purl.uniprot.org/citations/21636910http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21636910
http://purl.uniprot.org/citations/21636910http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21636910
http://purl.uniprot.org/uniprot/#_Q73RI0-mappedCitation-21636910http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21636910
http://purl.uniprot.org/uniprot/Q73RI0http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/21636910