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http://purl.uniprot.org/citations/21670305http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21670305http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21670305http://www.w3.org/2000/01/rdf-schema#comment"Signaling pathways essential for axon regeneration, but not for neuron development or function, are particularly well suited targets for therapeutic intervention. We find that the parallel PMK-3(p38) and KGB-1(JNK) MAPK pathways must be coordinately activated to promote axon regeneration. Axon regeneration fails if the activity of either pathway is absent. These two MAPKs are coregulated by the E3 ubiquitin ligase RPM-1(Phr1) via targeted degradation of the MAPKKKs DLK-1 and MLK-1 and by the MAPK phosphatase VHP-1(MKP7), which negatively regulates both PMK-3(p38) and KGB-1(JNK)."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1104830108"xsd:string
http://purl.uniprot.org/citations/21670305http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1104830108"xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Matsumoto K."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Matsumoto K."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Hisamoto N."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Hisamoto N."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Bastiani M."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Bastiani M."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Nix P."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/author"Nix P."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/pages"10738-10743"xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/pages"10738-10743"xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/title"Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/title"Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways."xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/volume"108"xsd:string
http://purl.uniprot.org/citations/21670305http://purl.uniprot.org/core/volume"108"xsd:string
http://purl.uniprot.org/citations/21670305http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21670305
http://purl.uniprot.org/citations/21670305http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21670305