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http://purl.uniprot.org/citations/21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21679708http://www.w3.org/2000/01/rdf-schema#comment"HVEM is a member of the TNF receptor superfamily that plays a role in the development of various inflammatory diseases. In this study, we show that HVEM deficiency attenuates adipose tissue inflammatory responses and glucose intolerance in diet-induced obesity. Feeding a high-fat diet (HFD) to HVEM-deficient mice elicited a reduction in the number of macrophages and T cells infiltrated into adipose tissue. Proinflammatory cytokine levels in the adipose tissue decreased in HFD-fed HVEM-deficient mice, while levels of the anti-inflammatory cytokine IL-10 increased. Moreover, glucose intolerance and insulin sensitivity were markedly improved in the HFD-fed HVEM-deficient mice. These findings indicate that HVEM may be a useful target for combating obesity-induced inflammatory responses and insulin resistance."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2011.05.057"xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Kim H.J."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Kim H.M."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Yu R."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Choi H.S."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Kim C.S."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Kawada T."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Kim B.S."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/author"Jeong C.S."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/pages"2285-2290"xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/title"HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance."xsd:string
http://purl.uniprot.org/citations/21679708http://purl.uniprot.org/core/volume"585"xsd:string
http://purl.uniprot.org/citations/21679708http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21679708
http://purl.uniprot.org/citations/21679708http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21679708
http://purl.uniprot.org/uniprot/#_A0A1W2P889-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_A0A1W2P6M8-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_A0A1W2P7D5-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_F6Y2U8-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_Q80WM9-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_Q3SXX1-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708
http://purl.uniprot.org/uniprot/#_Q71F55-mappedCitation-21679708http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21679708