http://purl.uniprot.org/citations/21679708 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21679708 | http://www.w3.org/2000/01/rdf-schema#comment | "HVEM is a member of the TNF receptor superfamily that plays a role in the development of various inflammatory diseases. In this study, we show that HVEM deficiency attenuates adipose tissue inflammatory responses and glucose intolerance in diet-induced obesity. Feeding a high-fat diet (HFD) to HVEM-deficient mice elicited a reduction in the number of macrophages and T cells infiltrated into adipose tissue. Proinflammatory cytokine levels in the adipose tissue decreased in HFD-fed HVEM-deficient mice, while levels of the anti-inflammatory cytokine IL-10 increased. Moreover, glucose intolerance and insulin sensitivity were markedly improved in the HFD-fed HVEM-deficient mice. These findings indicate that HVEM may be a useful target for combating obesity-induced inflammatory responses and insulin resistance."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2011.05.057"xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Kim H.J."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Kim H.M."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Yu R."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Choi H.S."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Kim C.S."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Kawada T."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Kim B.S."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/author | "Jeong C.S."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/pages | "2285-2290"xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/title | "HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance."xsd:string |
http://purl.uniprot.org/citations/21679708 | http://purl.uniprot.org/core/volume | "585"xsd:string |
http://purl.uniprot.org/citations/21679708 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21679708 |
http://purl.uniprot.org/citations/21679708 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21679708 |
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