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http://purl.uniprot.org/citations/2169439http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2169439http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2169439http://www.w3.org/2000/01/rdf-schema#comment"1. Angiotensin converting enzyme inhibitor has been isolated from the venom of Vipera aspis aspis by gel filtration and reverse phase HPLC. 2. The purified inhibitor is a decapeptide, whose amino-terminal is blocked, with mol. wt 1044 determined by fast atom bombardment mass spectrometry. 3. The peptide inhibited the conversion of angiotensin I to angiotensin II, and Ki values were determined to be 7.54 x 10(-4) and 1.36 x 10(-4) M, respectively, using Hip-His-Leu and Hip-Gly-Gly as substrates 4. The peptide also inhibited the degradation of bradykinin, induced hypotension in spontaneously hypertensive rats and caused an increase in capillary permeability in rabbits, however, it possessed no lethality."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.org/dc/terms/identifier"doi:10.1016/0020-711x(90)90013-s"xsd:string
http://purl.uniprot.org/citations/2169439http://purl.org/dc/terms/identifier"doi:10.1016/0020-711x(90)90013-s"xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/author"Komori Y."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/author"Komori Y."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/author"Sugihara H."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/author"Sugihara H."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/date"1990"xsd:gYear
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/name"Int. J. Biochem."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/name"Int. J. Biochem."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/pages"767-771"xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/pages"767-771"xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/title"Characterization of a new inhibitor for angiotensin converting enzyme from the venom of Vipera aspis aspis."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/title"Characterization of a new inhibitor for angiotensin converting enzyme from the venom of Vipera aspis aspis."xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/2169439http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/2169439http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2169439
http://purl.uniprot.org/citations/2169439http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2169439
http://purl.uniprot.org/citations/2169439http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2169439
http://purl.uniprot.org/citations/2169439http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2169439
http://purl.uniprot.org/uniprot/P31351http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/2169439
http://purl.uniprot.org/uniprot/#_kb.P31351_up.isolatedFrom_tissue.1109http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/2169439