RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21713679http://www.w3.org/2000/01/rdf-schema#comment"The exosome consists of a core of ten essential proteins that includes the ribonuclease Rrp44p and is present in both the cytoplasm and nucleus of eukaryotic cells. The cytoplasmic exosome has been extensively characterized in the budding yeast Saccharomyces cerevisiae and some characterization of its metazoan counterpart indicates that most functional aspects are conserved. These studies have implicated the cytoplasmic exosome in the turnover of normal cellular mRNAs, as well as several mRNA surveillance pathways. For this, the exosome needs a set of four proteins that do not partake in nuclear exosome functions. These cofactors presumably direct the exosome to specific cytoplasmic RNA substrates. Here, we review cofactors and functions of the cytoplasmic exosome and provide unanswered questions on the mechanisms of cytoplasmic exosome function."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.org/dc/terms/identifier"doi:10.1007/978-1-4419-7841-7_7"xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/author"Clark A."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/author"Schaeffer D."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/author"Tsanova B."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/author"van Hoof A."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/author"Klauer A.A."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/name"Adv Exp Med Biol"xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/pages"79-90"xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/title"Functions of the cytoplasmic exosome."xsd:string
http://purl.uniprot.org/citations/21713679http://purl.uniprot.org/core/volume"702"xsd:string
http://purl.uniprot.org/citations/21713679http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21713679
http://purl.uniprot.org/citations/21713679http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/21713679
http://purl.uniprot.org/uniprot/#_P53550-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_Q08162-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P22147-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P17883-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P47047-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_Q06151-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P30771-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P32769-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_P35207-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679
http://purl.uniprot.org/uniprot/#_Q02793-mappedCitation-21713679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/21713679