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http://purl.uniprot.org/citations/21722521http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21722521http://www.w3.org/2000/01/rdf-schema#comment"

Aim

To study the effects of CD74 gene on IFN-γR expression in myasthenia gravis thymic epithelial cell(TEC).

Methods

PCMV-CD74 transiently transfect to primary cultured TEC mediated with lipofectamine, the result of transfection and some autoimmune related genes such as IFN-γR were detected by real-time RT-PCR.

Results

Real-time quantitative RT-PCR results show that the mRNA expression level of IL-4R, IL-32, IFN-γR, ECGF1, HLA-A, HLA-DR increased significantly, with the high express ion of CD74 gene in thymic epithelial cells.

Conclusion

CD74 gene over-expression in TEC can increase IFN-γR mRNA expression."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/author"Du Y."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/author"Gao F."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/author"Zhang Q.Y."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/author"Li Q.R."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/author"Zang W.Q."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/name"Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi"xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/pages"730-732"xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/title"[Effects of CD74 gene on IFNgammaR gene expression in MG TEC]."xsd:string
http://purl.uniprot.org/citations/21722521http://purl.uniprot.org/core/volume"27"xsd:string
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