| http://purl.uniprot.org/citations/2173145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2173145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2173145 | http://www.w3.org/2000/01/rdf-schema#comment | "The Wilms tumor locus on chromosome 11p13 has been mapped to a region defined by overlapping, tumor-specific deletions. Complementary DNA clones representing transcripts of 2.5 (WIT-1) and 3.5 kb (WIT-2) mapping to this region were isolated from a kidney complementary DNA library. Expression of WIT-1 and WIT-2 was restricted to kidney and spleen. RNase protection revealed divergent transcription of WIT-1 and WIT-2, originating from a DNA region of less than 600 bp. Both transcripts were present at high concentrations in fetal kidney and at much reduced amounts in 5-year-old and adult kidneys. Eleven of 12 Wilms tumors classified as histopathologically heterogeneous exhibited absent or reduced expression of WIT-2, whereas only 4 of 14 histopathologically homogeneous tumors showed reduced expression. These data demonstrate a molecular basis for the pathogenetic heterogeneity in Wilms tumorigenesis."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.2173145"xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.2173145"xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Huang A."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Huang A."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Feinberg A.P."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Feinberg A.P."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Yeger H."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Yeger H."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Bonetta L."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Bonetta L."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Williams B.R."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Williams B.R."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Law D.J."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Law D.J."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Campbell C.E."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Campbell C.E."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Chilton-Macneill S."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Chilton-Macneill S."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Coppes M.J."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "Coppes M.J."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "McAndrews-Hill M.S."xsd:string |
| http://purl.uniprot.org/citations/2173145 | http://purl.uniprot.org/core/author | "McAndrews-Hill M.S."xsd:string |