| http://purl.uniprot.org/citations/21738226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21738226 | http://www.w3.org/2000/01/rdf-schema#comment | "Rad51 is a key enzyme involved in DNA double-strand break repair by homologous recombination. Here, we show that in response to DNA damage, budding yeast Rad51 is phosphorylated on Ser 192 in a manner that is primarily mediated by the DNA-damage-responsive protein kinase Mec1. We show that mutating Rad51 Ser 192 to Ala or Glu confers hypersensitivity to DNA damage and homologous-recombination defects. Furthermore, biochemical analyses indicate that Ser 192 is required for Rad51 adenosine triphosphate hydrolysis and DNA-binding activity in vitro, whereas mutation of Ser 192 does not interfere with Rad51 multimer formation. These data suggest a model in which Mec1-mediated phosphorylation of Rad51 Ser 192 in response to DNA damage controls Rad51 activity and DNA repair by homologous recombination."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2011.127"xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Jackson S.P."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Rice P.A."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Sung P."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Flott S."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Kwon Y."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/author | "Pigli Y.Z."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/name | "EMBO Rep"xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/pages | "833-839"xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/title | "Regulation of Rad51 function by phosphorylation."xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/21738226 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21738226 |
| http://purl.uniprot.org/citations/21738226 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21738226 |
| http://purl.uniprot.org/uniprot/P25454#attribution-E11670E0FEA493932C3ABF0CD2574325 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/21738226 |
| http://purl.uniprot.org/uniprot/#_A0A8H8ULW3-mappedCitation-21738226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21738226 |
| http://purl.uniprot.org/uniprot/#_P25454-mappedCitation-21738226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21738226 |
| http://purl.uniprot.org/uniprot/A0A8H8ULW3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21738226 |
| http://purl.uniprot.org/uniprot/P25454 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/21738226 |