| http://purl.uniprot.org/citations/21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21744989 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA-G and HLA-E are nonclassical human MHC class I molecules, which promote tolerance to NK cytotoxicity. MICA and MICB are known to enhance the functions of NK and T cells. However, the expression of these molecules has never been investigated in liver cancer. Using RT-PCR and western blot, we aimed to identify the expression of HLA-G, HLA-E, MICA and MICB in a panel of 41 tissues dissecting from liver cancer patients in China. HLA-G mRNA was expressed in 8 of 41 Human Hepatocellular Carcinoma (HCC) specimens and in 1 adjacent normal hepatocellular tissue. The expression of HLA-G protein was found in 7 of the 8 HLA-G mRNA-positive HCC tissues. HLA-E mRNA was up-regulated in 56% HCC specimens but the expression of HLA-E protein was only upregulated in 29% HCC tissues in comparison with their adjacent normal counterpart. MICA and MICB mRNA was decreased in 5% and 8% HCC specimens, while the expression of their proteins decreased in 21% and 24% HCC tissues. These results suggested that the expressions of HLA-G, HLA-E, MICA and MICB were differently up-regulated in HCC tissues. Furthermore, HLA-E and MICA/B genes showed obviously distinctive expression pattern at transcription and translation level."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.org/dc/terms/identifier | "doi:10.4149/neo_2011_05_371"xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Chen A."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Shen Y."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Xu L."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Shen C."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Xia M."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Yin Y."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Pan N."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Xie W."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/author | "Miao F."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/name | "Neoplasma"xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/pages | "371-376"xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/title | "Expression of the nonclassical HLA class I and MICA/B molecules in human hepatocellular carcinoma."xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/21744989 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21744989 |
| http://purl.uniprot.org/citations/21744989 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21744989 |
| http://purl.uniprot.org/uniprot/#_A0A0F6UUZ2-mappedCitation-21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21744989 |
| http://purl.uniprot.org/uniprot/#_A0A0F7WBW2-mappedCitation-21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21744989 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21744989 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21744989 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-21744989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21744989 |