| http://purl.uniprot.org/citations/21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21762747 | http://www.w3.org/2000/01/rdf-schema#comment | "The significance of upregulated soluble human leukocyte antigen-G (sHLA-G) expression under various pathologic conditions has been discussed. In this study, we evaluated the potential significance of plasma sHLA-G expression in patients with hepatitis B virus (HBV) infection. The study included 90 acute hepatitis B patients (AHB), 131 chronic hepatitis B patients (CHB), 152 resolved hepatitis B individuals (RHB), and 129 normal controls. sHLA-G were determined using enzyme-linked immunosorbent assay. A receiver operating characteristic (ROC) curve was used to evaluate the feasibility of plasma sHLA-G as a biomarker for distinguishing patients with HBV infection. sHLA-G levels in AHB (median, 193.1 U/mL; p < 0.001), CHB (median, 324.6 U/mL; p < 0.001), and RHB (median, 14.8 U/mL; p = 0.006) patients was much higher than that in normal controls (median, 9.0 U/mL). A significant difference for sHLA-G levels was also observed between patients with HBV infection (AHB vs CHB, AHB vs RHB, and CHB vs RHB; all p < 0.001). The area under the ROC curve for sHLA-G levels was 1.000 (p < 0.001) for AHB, 0.993 (p < 0.001) for CHB, and 0.604 (p = 0.003) for RHB patients versus normal controls, respectively. Data also indicated that the percentage of CD4(+)CD25(+)FoxP3(+) T regulatory cells and HLA-G(+)CD14(+) monocytes was significantly increased in AHB and CHB patients compared with normal controls (all p < 0.001). Our findings indicated that induction of HLA-G expression may play a role in HBV immune evasion and sHLA-G levels could be a useful biomarker in HBV infection."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2011.06.012"xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Lin A."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Chen S.Y."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Yan W.H."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Shi W.W."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Zhang J.G."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Bao W.G."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/author | "Xu D.P."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/pages | "1068-1073"xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/title | "Plasma soluble human leukocyte antigen-G expression is a potential clinical biomarker in patients with hepatitis B virus infection."xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://purl.uniprot.org/core/volume | "72"xsd:string |
| http://purl.uniprot.org/citations/21762747 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21762747 |
| http://purl.uniprot.org/citations/21762747 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21762747 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y1-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y2-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y3-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |
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| http://purl.uniprot.org/uniprot/#_A0A0H4M9Z1-mappedCitation-21762747 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21762747 |