http://purl.uniprot.org/citations/21788473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21788473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/21788473 | http://www.w3.org/2000/01/rdf-schema#comment | "A carbapenem-resistant Pseudomonas aeruginosa strain (PA41437) susceptible to expanded-spectrum cephalosporins was recovered from several consecutive lower-respiratory-tract specimens of a patient who developed a ventilator-associated pneumonia while hospitalized in an intensive care unit. Cloning experiments identified OXA-198, a new class D β-lactamase which was weakly related (less than 45% amino acid identity) to other class D β-lactamases. Expression in Escherichia coli TOP10 and in P. aeruginosa PAO1 led to transformants that were resistant to ticarcillin and showed reduced susceptibility to carbapenems and cefepime. The bla(OXA-198) gene was harbored by a class 1 integron carried by a ca. 46-kb nontypeable plasmid. This study describes a novel class D β-lactamase involved in carbapenem resistance in P. aeruginosa."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.org/dc/terms/identifier | "doi:10.1128/AAC.00522-11"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.org/dc/terms/identifier | "doi:10.1128/aac.00522-11"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Galleni M."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Galleni M."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Bebrone C."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Bebrone C."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Bogaerts P."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Bogaerts P."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Glupczynski Y."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "Glupczynski Y."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "El Garch F."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/author | "El Garch F."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/name | "Antimicrob. Agents Chemother."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/name | "Antimicrob Agents Chemother"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/pages | "4828-4833"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/pages | "4828-4833"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/title | "OXA-198, an Acquired Carbapenem-Hydrolyzing Class D {beta}-Lactamase from Pseudomonas aeruginosa."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/title | "OXA-198, an acquired carbapenem-hydrolyzing class D beta-lactamase from Pseudomonas aeruginosa."xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/volume | "55"xsd:string |
http://purl.uniprot.org/citations/21788473 | http://purl.uniprot.org/core/volume | "55"xsd:string |