| http://purl.uniprot.org/citations/21808284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21808284 | http://www.w3.org/2000/01/rdf-schema#comment | "We conducted gender-stratified analyses on a systems-based candidate gene study of 53 regions involved in nicotinic response and the brain-reward pathway in two randomized clinical trials of smoking cessation treatments (placebo, bupropion, transdermal and nasal spray nicotine replacement therapy). We adjusted P-values for multiple correlated tests, and used a Bonferroni-corrected α-level of 5 × 10(-4) to determine system-wide significance. Four single-nucleotide polymorphisms (rs12021667, rs12027267, rs6702335, rs12039988; r2 > 0.98) in erythrocyte membrane protein band 4.1 (EPB41) had a significant male-specific marginal association with smoking abstinence (odds ratio (OR) = 0.5; 95% confidence interval (CI): 0.3-0.6) at end of treatment (adjusted P < 6 × 10(-5)). rs806365 in cannabinoid receptor 1 (CNR1) had a significant male-specific gene-treatment interaction at 6-month follow-up (adjusted P = 3.9 × 10(-5)); within males using nasal spray, rs806365 was associated with a decrease in odds of abstinence (OR = 0.04; 95% CI: 0.01-0.2). While the role of CNR1 in substance abuse has been well studied, we report EPB41 for the first time in the nicotine literature."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.org/dc/terms/identifier | "doi:10.1038/tpj.2011.30"xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Liu J."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Li D."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Thomas P."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Lee W."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Tyndale R.F."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Bergen A.W."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Conti D.V."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Lerman C."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Swan G.E."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/author | "Benowitz N.L."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/name | "Pharmacogenomics J"xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/pages | "521-532"xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/title | "Gender-stratified gene and gene-treatment interactions in smoking cessation."xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/21808284 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/21808284 |
| http://purl.uniprot.org/citations/21808284 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/21808284 |
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| http://purl.uniprot.org/uniprot/#_A0A2R8YD30-mappedCitation-21808284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21808284 |
| http://purl.uniprot.org/uniprot/#_P11171-mappedCitation-21808284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21808284 |
| http://purl.uniprot.org/uniprot/#_B7Z5L2-mappedCitation-21808284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21808284 |
| http://purl.uniprot.org/uniprot/#_B7Z627-mappedCitation-21808284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/21808284 |