| http://purl.uniprot.org/citations/2183176 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2183176 | http://www.w3.org/2000/01/rdf-schema#comment | "Eleven mutations resulting in partially deleted or truncated LEU3 protein were generated by linker insertion or other modifications at restriction sites, deletion of restriction fragments, or oligonucleotide-directed mutagenesis. Functional studies of these mutants showed the following: (i) A specific DNA binding region is contained within the 173 N-terminal residues, but other regions of the protein are required for optimal binding. (ii) Activation of LEU2 expression depends on the C-terminal 113 residues of the LEU3 protein. (iii) Deletion of part or all of a central section of LEU3 eliminates the ability of the LEU3 protein to respond to the co-activator alpha-isopropylmalate, i.e. creates an unmodulated activator. (iv) Overproduction of unmodulated activator slows down cell growth. (v) Specific deletion of two short acidic regions, including one with net charge - 19, has only minor effects on activation and modulation."xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/18.2.291"xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/author | "Kohlhaw G.B."xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/author | "Bai Y.L."xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/author | "Zhou K.M."xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/name | "Nucleic Acids Res"xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/pages | "291-298"xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/title | "Yeast regulatory protein LEU3: a structure-function analysis."xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/2183176 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2183176 |
| http://purl.uniprot.org/citations/2183176 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2183176 |
| http://purl.uniprot.org/uniprot/P08638#attribution-C1201AA41A76ED703F9EC7400A24339B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/2183176 |
| http://purl.uniprot.org/uniprot/#_P08638-mappedCitation-2183176 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/2183176 |
| http://purl.uniprot.org/uniprot/P08638 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/2183176 |