| http://purl.uniprot.org/citations/2183353 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2183353 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2183353 | http://www.w3.org/2000/01/rdf-schema#comment | "The product of the c-abl proto-oncogene (c-Abl) is phosphorylated on three sites during interphase and seven additional sites during mitosis. Two interphase and all mitotic c-Abl sites are phosphorylated by cdc2 kinase isolated from either interphase or mitotic cells, with the mitotic cdc2 having an 11-fold higher activity. Inhibition of phosphatases with okadaic acid in interphase cells leads to the phosphorylation of c-Abl mitotic sites, indicating that those sites are preferentially dephosphorylated during interphase. The differential phosphorylation of c-Abl in the cell cycle is therefore determined by an equilibrium between cdc2 kinase and protein phosphatase activities. Treatment of interphase cells with okadaic acid leads to a rounded morphology similar to that observed during mitosis."xsd:string |
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| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/author | "Wang J.Y."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/author | "Wang J.Y."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/author | "Kipreos E.T."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/author | "Kipreos E.T."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/pages | "217-220"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/pages | "217-220"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/title | "Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/title | "Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity."xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/volume | "248"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://purl.uniprot.org/core/volume | "248"xsd:string |
| http://purl.uniprot.org/citations/2183353 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2183353 |
| http://purl.uniprot.org/citations/2183353 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2183353 |
| http://purl.uniprot.org/citations/2183353 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2183353 |
| http://purl.uniprot.org/citations/2183353 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2183353 |
| http://purl.uniprot.org/uniprot/P00519 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2183353 |
| http://purl.uniprot.org/uniprot/P00520 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2183353 |