| http://purl.uniprot.org/citations/21842124 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21842124 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate the relationship between polymorphisms in the estrogen receptor-α (ERα) gene and unexplained female infertility, restriction fragment length polymorphism (RFLP) analysis of ERα was employed in 150 females with idiopathic infertility (study group) and 150 healthy, age-matched females of proven fertility (control group). The results showed that the ERα allele frequencies differed significantly between the study and control groups (P=0.001). The allele identified by PvuII (P) restriction was detected more frequently in the study group (49.0% of individuals) compared to the control group (31.0%; P=0.001), while the allele identified by XbaI (X) restriction was detected less frequently in the study group (19.7%) compared to the control group (35.7%, P=0.001). A similar phenomenon was observed for the distribution of the TA alleles. The TA13 allele was more common in the study group (24.7 vs. 6.7% in controls; P=0.001), while the TA15 allele was less common in the study group (15.3 vs. 27.3% in controls; P=0.034). To conclude, polymorphisms in the ERα gene are associated with idiopathic female infertility. In particular, the P and TA13 alleles may represent significant risk factors, while the X and TA15 alleles may be protective factors."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.org/dc/terms/identifier | "doi:10.3892/mmr.2011.551"xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/author | "Xu K.Y."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/author | "Fang L.Y."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/author | "Qi X.L."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/author | "Tao X.R."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/author | "Du J.W."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/name | "Mol Med Rep"xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/pages | "1239-1242"xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/title | "Polymorphisms in estrogen receptor-alpha are associated with idiopathic female infertility."xsd:string |
| http://purl.uniprot.org/citations/21842124 | http://purl.uniprot.org/core/volume | "4"xsd:string |
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