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http://purl.uniprot.org/citations/21847104http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21847104http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21847104http://www.w3.org/2000/01/rdf-schema#comment"It is well known that the parallel order of microtubules in the plant cell cortex defines the direction of cell expansion, yet it remains unclear how microtubule orientation is controlled, especially on a cell-wide basis. Here we show through 4D imaging and computational modelling that plant cell polyhedral geometry provides spatial input that determines array orientation and heterogeneity. Microtubules depolymerize when encountering sharp cell edges head-on, whereas those oriented parallel to those sharp edges remain. Edge-induced microtubule depolymerization, however, is overcome by the microtubule-associated protein CLASP, which accumulates at specific cell edges, enables microtubule growth around sharp edges and promotes formation of microtubule bundles that span adjacent cell faces. By computationally modelling dynamic 'microtubules on a cube' with edges differentially permissive to microtubule passage, we show that the CLASP-edge complex is a 'tuneable' microtubule organizer, with the inherent flexibility to generate the numerous cortical array patterns observed in nature."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.org/dc/terms/identifier"doi:10.1038/ncomms1444"xsd:string
http://purl.uniprot.org/citations/21847104http://purl.org/dc/terms/identifier"doi:10.1038/ncomms1444"xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Ambrose C."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Ambrose C."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Wasteneys G.O."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Wasteneys G.O."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Allard J.F."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Allard J.F."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Cytrynbaum E.N."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/author"Cytrynbaum E.N."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/name"Nat. Commun."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/name"Nat. Commun."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/pages"430"xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/pages"430"xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/title"A CLASP-modulated cell edge barrier mechanism drives cell-wide cortical microtubule organization in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/title"A CLASP-modulated cell edge barrier mechanism drives cell-wide cortical microtubule organization in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/volume"2"xsd:string
http://purl.uniprot.org/citations/21847104http://purl.uniprot.org/core/volume"2"xsd:string
http://purl.uniprot.org/citations/21847104http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21847104
http://purl.uniprot.org/citations/21847104http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/21847104